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Myostatin (also known as growth differentiation factor 8, abbreviated GDF8) is a protein that in humans is encoded by the MSTN gene. Myostatin is a myokine that is produced and released by myocytes and acts on muscle cells to inhibit muscle growth. Myostatin is a secreted growth differentiation factor that is a member of the TGF beta protein family.

Antibodies. The injection of MSTN neutralizing antibodies is known to significantly increase muscle mass (by up to 17%) in aged mice. The administration of neutralizing。

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